7-(4-Chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone

Basic Information

CAS No.	120004-79-7
EC No.	Not available
Linear Formula	C13H16ClNO2
Molecular Weight	253.72
Appearance	White to off-white crystalline powder
Melting Point	100-102 °C (lit.)
Boiling point	449 °C (lit.)
Density	1.19 g/mL (lit.)
Solubility	Soluble in organic solvents such as DMSO, methanol, and dichloromethane; limited solubility in water
Storage Conditions	Keep in a tightly closed container, protected from light, at 2-8 °C
Chemical Structure

Key Applications

• Pharmaceutical intermediate: A primary building block in the multi-step synthesis of aripiprazole, an atypical antipsychotic API, and an important component within Aripiprazole and Fluvoxamine intermediates for CNS-focused pharmaceutical development.

• API intermediate: Enables efficient introduction of the chlorobutoxy side chain required for pharmacologically active quinolinone derivatives, especially in the preparation of CNS drug intermediates for antipsychotic synthesis.

• Heterocyclic synthesis: Serves as a functionalized dihydroquinolinone scaffold for constructing nitrogen-containing heterocyclic molecules in pharmaceutical and fine chemical synthesis.

• Medicinal chemistry research: Widely applied in laboratory route scouting and analog preparation within CNS drug discovery and process evaluation programs.

• Process development: Supports scale-up and optimization studies for commercial manufacture of high-purity pharmaceutical intermediates for API synthesis.

• Consistent product quality: Batch-to-batch consistency verified through routine analytical controls, meeting requirements for pharmaceutical intermediate applications.

• Stable global supply: Reliable logistics network ensures timely delivery for laboratory, pilot, and commercial scale orders worldwide.

• SDS and COA support: Comprehensive documentation including SDS and COA provided upon request to facilitate regulatory compliance and quality review.

• Packaging and technical service: Flexible options such as 1 kg, 5 kg, or 25 kg fiber drums with PE liner, backed by responsive technical communication.