1-(2,3-dichlorophenyl)piperazine dihydrochloride (2,3-DCPP HCl)

Basic Information

CAS No.	119532-26-2
EC No.	Not available
Linear Formula	C10H12Cl2N2·HCl
Molecular Weight	267.58
Appearance	White to off-white crystalline powder
Melting Point	243-247 °C (lit.)
Boiling point	Not available (typical reference)
Density	Not available (typical reference)
Solubility	Soluble in DMSO, DMF, and methanol; slightly soluble in water and ethanol
Storage Conditions	Store in a tightly closed container at 2-8°C, protected from moisture
Chemical Structure

Key Applications

• Pharmaceutical intermediate: A key building block for the production of aripiprazole and related antipsychotic active pharmaceutical ingredients, and an important component within Aripiprazole and Fluvoxamine intermediates for CNS-focused pharmaceutical development.

• API intermediate: Enables efficient attachment of the arylpiperazine moiety essential in CNS drug synthesis, especially among CNS drug intermediates used in antipsychotic development.

• Heterocyclic synthesis: Provides a functionalized piperazine scaffold for constructing complex nitrogen-containing heterocyclic compounds, making it relevant to piperazine and piperidine intermediates in pharmaceutical synthesis.

• Medicinal chemistry research: Utilized in analog synthesis and structure-activity relationship studies for neuropsychiatric drug candidates and related small-molecule discovery programs.

• Process development: Supports route optimization and scale-up activities for commercial manufacture of high-purity pharmaceutical intermediates for API synthesis.

• Consistent product quality: High-purity specifications maintained through rigorous in-house testing to ensure batch-to-batch reliability for pharmaceutical applications.

• Stable global supply: Established supply chain delivers consistent availability from laboratory to commercial quantities for international customers.

• SDS and COA support: Full product documentation including SDS and COA supplied upon request to streamline quality assurance and regulatory processes.

• Packaging and technical service: Customized packaging in 1 kg, 5 kg, or 25 kg fiber drums with PE liner, supported by responsive technical assistance.