tert-Butyl 4-(1H-1,3-benzodiazol-2-yl)piperidine-1-carboxylate

Basic Information

CAS No.	953071-73-3
EC No.	Not available
Linear Formula	C17H23N3O2
Molecular Weight	301.38
Appearance	White to off-white solid
Melting Point	Not available (typical reference)
Boiling point	497 ± 38 °C (predicted, lit.)
Density	Not available (typical reference)
Solubility	Soluble in organic solvents such as DMSO, methanol, and dichloromethane; limited solubility in water
Storage Conditions	Sealed in dry container at 2-8°C, protected from light and moisture
Chemical Structure

Key Applications

• Pharmaceutical intermediate: A key protected intermediate in pathways associated with bilastine and related antihistamine compound synthesis, and an important component within Bilastine and specialty antihistamine intermediates for pharmaceutical development.

• API intermediate: Facilitates incorporation of the benzimidazole-piperidine motif into active pharmaceutical ingredients after deprotection, making it relevant to piperazine and piperidine intermediates in API synthesis.

• Heterocyclic synthesis: Provides a Boc-masked piperidine linked to benzimidazole for constructing fused heterocyclic frameworks, especially among quinazolinone, benzimidazole and fused heterocycle intermediates.

• Medicinal chemistry research: Utilized in analog design and structure modification studies targeting therapeutic scaffolds and related antihistamine discovery programs.

• Process development: Supports evaluation of deprotection conditions and scale-up strategies for pharmaceutical manufacturing routes and pharmaceutical intermediates for API synthesis.

• Consistent product quality: High purity maintained with batch-specific analytical data to ensure suitability for precise synthetic applications.

• Stable global supply: Proven logistics framework guarantees on-time delivery across laboratory to pilot-scale requirements worldwide.

• SDS and COA support: SDS, COA, and related certificates supplied readily to assist with quality assessment and compliance procedures.

• Packaging and technical service: Flexible packaging choices like 1kg, 5kg, or 25kg in fiber drums with PE liners, paired with attentive technical support.