5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone

5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone is a trifluoromethyl-substituted aryl ketone with a methoxy-terminated alkyl chain. The ketone functionality allows for transformations such as oxime formation in multi-step syntheses.

Basic Information

CAS No.	61718-80-7
EC No.	Not available
Linear Formula	C13H15F3O2
Molecular Weight	260.25
Appearance	White to off-white solid
Melting Point	50-52 °C (lit.)
Boiling point	318.7±42.0 °C (Predicted)
Density	1.147±0.06 g/cm³ (Predicted)
Solubility	Soluble in chloroform, methanol; slightly soluble in water (typical reference)
Storage Conditions	Sealed in dry, room temperature
Chemical Structure

Key Applications

• Pharmaceutical intermediate: A key precursor in the synthesis of fluvoxamine, an SSRI antidepressant, via oxime intermediate formation, and an important building block within Aripiprazole and Fluvoxamine intermediates for CNS-focused API development.

• API intermediate: Used in the production of active pharmaceutical ingredients featuring trifluoromethylated aryl ketones, making it relevant to fluorinated pharmaceutical intermediates in medicinal chemistry and process synthesis.

• Aromatic compound synthesis: Provides a fluorinated aromatic scaffold for ketone-based transformations in organic synthesis, especially in the development of CNS drug intermediates and related fine chemicals.

• Laboratory research: Employed in medicinal chemistry for analog development, impurity studies, and route evaluation involving fluorinated small molecules.

• Process development: Applied in route optimization and scale-up for efficient manufacturing of fine chemical intermediates and pharmaceutical intermediates for API synthesis.

• High batch consistency: Purity and uniformity ensured through rigorous quality controls tailored for pharmaceutical intermediate requirements.

• Stable international supply: Dependable logistics channels supporting global export from research to production quantities.

• Documentation provision: SDS, COA, and related certificates available to meet sourcing and compliance standards.

• Packaging flexibility: Options including 1kg/5kg/25kg fiber drums with PE liners or customized packaging, with responsive technical support.