1-(2,3-Dichlorophenyl)piperazine

1-(2,3-Dichlorophenyl)piperazine is an arylpiperazine derivative used as an organic intermediate in selected pharmaceutical intermediate, fine chemical, and specialty synthesis routes. Its structure contains a piperazine ring substituted with a 2,3-dichlorophenyl group, providing an N-aryl piperazine framework for downstream transformation.

Basic Information

CAS No.	41202-77-1
EC No.	609-896-3
Linear Formula	C10H12Cl2N2
Molecular Weight	231.12
Appearance	White to off-white or light brown crystalline solid
Melting Point	242-244 °C (lit.)
Boiling point	365 °C (Predicted)
Density	1.272 g/cm³ (Predicted)
Solubility	Soluble in chloroform and dichloromethane
Storage Conditions	Keep in a cool, dry place, sealed tightly, protected from light
Chemical Structure

Key Applications

• Pharmaceutical intermediate: Used as an arylpiperazine intermediate in selected pharmaceutical intermediate synthesis routes, depending on the target structure and specification requirements.

• Organic synthesis intermediate: Can support the introduction of a 2,3-dichlorophenylpiperazine structure through suitable alkylation, coupling, or further functionalization routes.

• Heterocyclic synthesis: May be evaluated in route development involving piperazine-containing nitrogen heterocyclic intermediates.

• Research and route development: Suitable for exploratory synthesis, route screening, and intermediate evaluation involving substituted arylpiperazine structures.

• Specialty synthesis applications: May support process evaluation for fine chemical and specialty intermediate projects where dichlorophenylpiperazine functionality is required.

Related Heterocycle Intermediates

Buyers sourcing aryl, benzyl, or N-substituted piperazine derivatives may also review related piperazine intermediates such as 1-Phenylpiperazine CAS 92-54-6, 1-Benzylpiperazine CAS 2759-28-6, and 1-(2-Pyridyl)piperazine CAS 34803-66-2.

For related chloroalkyl, hydroxyethyl, or cycloalkyl piperazine intermediates, buyers may also compare 1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride CAS 2031-23-4, 1-(2-Hydroxyethyl)piperazine CAS 103-76-4, and 1-Cyclohexylpiperazine CAS 17766-28-8.

• Sourcing feasibility review: Availability, lead time, and order quantity are confirmed according to the specific product, supplier batch, current market conditions, and destination requirements.

• SDS and COA support: Available safety data sheets and certificates of analysis can be provided upon request, subject to the specific supplier, batch, and grade.

• Regulatory and export review: Applicable controls, import restrictions, documentation needs, and shipment feasibility should be reviewed according to the product, destination market, and intended use.

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