4-Hydroxypiperidine

4-Hydroxypiperidine is a hydroxyl-functional piperidine derivative used as an organic intermediate in selected pharmaceutical intermediate, fine chemical, and specialty synthesis routes. Its structure contains a saturated piperidine ring with a hydroxyl group at the 4-position, providing a useful functional handle for downstream transformation.

Basic Information

CAS No.	5382-16-1
EC No.	226-373-1
Linear Formula	C5H11NO
Molecular Weight	101.15
Appearance	White to off-white crystalline powder or solid
Melting Point	86-90 °C (lit.)
Boiling point	108-114 °C at 10 mmHg (lit.)
Density	Not available (typical reference)
Solubility	Soluble in water and common organic solvents
Storage Conditions	Store in a tightly closed container in a cool, dry place, protected from moisture and light
Chemical Structure

Key Applications

• Organic synthesis intermediate: Can be used as a hydroxypiperidine intermediate in selected organic synthesis routes involving alcohol derivatization, substitution, or further functionalization.

• Pharmaceutical intermediate: Used as a piperidine-based intermediate in selected pharmaceutical intermediate synthesis routes, depending on the target structure and specification requirements.

• Heterocyclic synthesis: May be evaluated in route development involving saturated nitrogen heterocycles and functionalized piperidine derivatives.

• Research and route development: Suitable for exploratory synthesis, route screening, and intermediate evaluation involving hydroxyl-functional piperidine structures.

• Specialty synthesis applications: May support process evaluation for fine chemical and specialty intermediate projects where 4-substituted piperidine functionality is required.

Related Heterocycle Intermediates

Buyers sourcing hydroxypiperidine or hydroxyalkyl piperidine derivatives may also review related piperidine intermediates such as 1-(2-Hydroxyethyl)piperidine CAS 3040-44-6, 1-Piperidinepropanol CAS 104-58-5, and 1-(3-Chloropropyl)piperidin-4-ol CAS 145285-36-5.

• Sourcing feasibility review: Availability, lead time, and order quantity are confirmed according to the specific product, supplier batch, current market conditions, and destination requirements.

• SDS and COA support: Available safety data sheets and certificates of analysis can be provided upon request, subject to the specific supplier, batch, and grade.

• Documentation and export review: Documentation needs, import requirements, and shipment feasibility should be reviewed according to the product, destination market, and intended use.

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