1-Chloro-4-methoxybutane

1-Chloro-4-methoxybutane is a monochloroalkyl methyl ether with a four-carbon chain linking the functional groups. This structure provides reactivity at the chloro terminus while the methoxy offers polarity and protection in synthetic sequences.

Basic Information

CAS No.	17913-18-7
EC No.	241-858-8
Linear Formula	C5H11ClO
Molecular Weight	122.59
Appearance	Colorless to pale yellow liquid
Melting Point	Not available (typical reference)
Boiling point	138-143 °C (lit.)
Density	1.0±0.1 g/mL at 20 °C (Predicted)
Solubility	Soluble in organic solvents; limited in water (typical reference)
Storage Conditions	Keep in a tightly closed container in a cool, dry place, room temperature
Chemical Structure

Key Applications

• Pharmaceutical intermediate: Serves as an alkylating agent in the synthesis of active pharmaceutical ingredients requiring methoxyalkyl chains, including intermediates relevant to Aripiprazole and Fluvoxamine intermediates in CNS-focused pharmaceutical development.

• Organic synthesis intermediate: Used for introducing protected ether linkages in multi-step organic preparations, especially within CNS drug intermediates and related medicinal chemistry programs.

• Functional molecule construction: Provides a bifunctional synthon for chain elongation and functionalization in fine chemical synthesis and downstream pharmaceutical intermediate design.

• Laboratory research: Applied in exploratory synthesis for novel compounds with alkoxyalkyl motifs and related small-molecule screening projects.

• Process development: Employed in route scouting and optimization for scalable production of specialty intermediates and pharmaceutical intermediates for API synthesis.

• Material quality reliability: Consistent purity and batch control through standard testing protocols suited to pharmaceutical intermediate standards.

• Export supply stability: Reliable international shipping arrangements ensuring timely delivery for various procurement volumes.

• SDS COA availability: Comprehensive safety data and analysis certificates supplied to support quality assurance and regulatory needs.

• Packaging and technical assistance: Flexible options such as 1kg/5kg/25kg HDPE drums or cartons with inner bags, along with expert technical communication.