Ruthenium on Carbon

Basic Information of Ruthenium on Carbon

CAS No.	7440-18-8 (Ru); support material varies
EC No.	231-127-1 (Ru)
Chemical Formula	Ru on activated carbon
Molecular Weight	101.07 g/mol (Ru basis)
Appearance	Black to dark gray powder
Odor	Odorless
Melting point	Not applicable (support decomposes; Ru melts at 2334 °C)
Boiling point	Not applicable
Density	approx. 0.4–0.8 g/cm³ (bulk density, loading-dependent)
Solubility	Insoluble in water and organic solvents
Nature (hazards)	Combustible solid (carbon support), may cause respiratory irritation when dust is inhaled, harmful if dust is inhaled in large quantities
RIDADR	Not regulated (non-hazardous for transport in many classifications; consult SDS for specific handling)
Chemical Structure

Primary Applications of Ruthenium on Carbon

Ruthenium on Carbon excels as a selective and robust heterogeneous catalyst for demanding hydrogenation and hydrogenolysis in high-value chemical manufacturing.

1. Aromatic Ring Hydrogenation
   Provides efficient saturation of benzene rings and heterocycles under moderate conditions, producing cyclohexane derivatives for agrochemicals, polymers, and performance chemicals.

2. Nitro Group Reduction to Amines
   Delivers clean, high-yield conversion of aromatic and aliphatic nitro compounds to primary amines, a critical step in dyes, pesticides, and pharmaceutical intermediate manufacturing.

3. Carbonyl & Imine Reduction
   Catalyzes selective hydrogenation of ketones, aldehydes, and imines to alcohols or amines, offering excellent selectivity in the presence of other reducible groups.

4. Debenzylation & Hydrogenolysis
   Enables selective removal of benzyl protecting groups with high functional group tolerance, essential for multi-step synthesis in medicinal chemistry.

5. Selective Alkene & Alkyne Hydrogenation
   Supports partial or complete reduction of unsaturated bonds with superior poison resistance, ideal for sensitive substrates in natural product and API synthesis.

6. Fine Chemical & API Manufacturing
   Widely applied in GMP processes for reduction and deprotection steps, offering scalability, easy catalyst removal, and high reproducibility.

• Optimized Ru Dispersion & Activity
  Advanced impregnation technology ensures uniform Ru particle size and high active surface area for maximum turnover frequency and selectivity.

• Custom Catalyst Formulations
  Tailored Ru loadings, support types, reduction states, and additives to precisely match your substrate, solvent system, and reaction conditions.

• Consistent Batch-to-Batch Reproducibility
  Rigorous testing (ICP, BET, XRD, activity assays) guarantees low variation and predictable scale-up performance.

• Secure Ruthenium Supply Chain
  Responsible sourcing, strategic inventory, and transparent pricing mitigate market volatility and ensure uninterrupted availability.

• Technical & Regulatory Support
  Expert guidance on catalyst activation, poison mitigation, recycling, and full documentation (COA, REACH, SDS) for seamless integration into GMP and fine chemical operations.

Hazards Classification

• GHS Classification: Specific Target Organ Toxicity, Single Exposure (respiratory tract irritation) (Category 3); Combustible dust hazard; Aquatic Chronic (Category 3)

• Hazard Statements: H335: May cause respiratory irritation; H413: May cause long lasting harmful effects to aquatic life

• UN Number: Not regulated

• Hazard Class: Not classified as hazardous for transport

• Packing Group: Not applicable