N,N-Diisopropylethylamine (DIPEA)

N,N-Diisopropylethylamine CAS 7087-68-5 for Organic Synthesis Base Applications

N,N-Diisopropylethylamine, also known as DIPEA or Hünig's Base, is a sterically hindered tertiary amine base used in organic synthesis. Its nitrogen atom is substituted with two isopropyl groups and one ethyl group, giving the molecule significant steric hindrance around the amine center.

Unlike tertiary amino alcohols, DIPEA does not contain hydroxyl functionality. It is mainly evaluated as a hindered amine base, acid scavenger or process reagent in organic synthesis routes. In B2B sourcing, buyers usually need to confirm assay, water content, appearance, color, secondary amine impurities, residual solvents, odor, flammability, packaging, transport classification and documentation availability before purchase.

Basic Information

The following information is provided as general product reference. Final specification, test method, hazard classification, packaging, storage conditions and documentation should be confirmed according to the actual batch and supplier information.

CAS No.	7087-68-5
EC No.	230-392-0
Linear Formula	C8H19N
Molecular Weight	129.24
Appearance	Colorless clear liquid
Odor	Strong characteristic amine odor
Melting Point	<-50°C (lit.)
Boiling Point	127°C (lit.)
Density	0.742 g/mL at 25°C (lit.)
Solubility	Slightly soluble in water; miscible with many common organic solvents
Flash Point	6°C
Transport Reference	UN 2734, Class 3, Packing Group II. Final transport classification should be confirmed according to the latest SDS, DGM or shipment documents before order confirmation.
Chemical Structure

Key Applications

• Hindered amine base: Used as a sterically hindered tertiary amine base in organic synthesis where basicity is required and nucleophilic participation should be limited.

• Acid scavenger: May be used to neutralize acids generated during selected alkylation, acylation, protection, coupling or halogenation-related reaction steps.

• Organic synthesis reagent: Suitable for fine chemical synthesis and specialty organic synthesis routes where a tertiary amine base is required.

• Peptide and coupling chemistry support: May be evaluated as a base in selected peptide coupling or organic coupling reactions, subject to process conditions and specification requirements.

• Process development: Can support laboratory evaluation, route screening and process optimization for organic synthesis projects.

• Salt formation and pH control: The tertiary amine structure may support selected routes requiring base-mediated control, salt formation or acid neutralization.

Sourcing and Documentation Support

• Specification confirmation: Assay, appearance, color, water content, secondary amine impurities, residual solvents and odor profile can be reviewed according to buyer requirements and supplier confirmation.

• COA and SDS support: COA and SDS may be provided for confirmed products, subject to product, batch and supplier confirmation.

• Packaging review: Packaging options can be checked according to product properties, order quantity, flammability, odor, moisture sensitivity, storage requirements and transport classification.

• Export and logistics discussion: Shipment feasibility, dangerous goods classification, trade term and destination requirements should be confirmed case by case before quotation or shipment.

Packaging and Logistics Considerations

N,N-Diisopropylethylamine is commonly handled as a flammable liquid amine material with strong characteristic odor. Suitable packaging should be confirmed according to product properties, order quantity, hazard classification, storage conditions, supplier specification and transport route.

Packaging may include small bottles, small drums, 25 L drums, 200 L drums or other suitable formats, subject to supplier confirmation. For DIPEA, packaging tightness, odor control, moisture protection, flammable liquid handling and dangerous goods requirements should be reviewed before shipment.

Sea, air, courier, LCL or FCL shipment feasibility should be evaluated case by case according to the latest SDS, transport classification, package size and destination requirements. Import clearance, local duties, taxes and destination compliance should be confirmed by the buyer or their appointed import agent.

Common trade terms may include FOB China port, FCA warehouse, CFR/CIF destination port or DAP destination where applicable. Final shipment arrangement depends on product classification, order quantity, destination and buyer import capability.

Safety and Storage Information

The following safety information is for general reference only. Final hazard classification, handling requirements, storage conditions, UN number, packing group and transport conditions must be confirmed according to the latest SDS, dangerous goods classification report and shipment documents.

• General hazard profile: DIPEA may present flammable, corrosive and harmful hazard characteristics. Handle only with appropriate personal protective equipment and engineering controls.

• Storage: Store in a tightly closed container in a cool, dry and well-ventilated place. Keep away from ignition sources, heat, oxidizing agents, acids and incompatible materials.

• Handling: Avoid direct contact with skin, eyes and clothing. Avoid inhalation of vapor. Use suitable gloves, eye protection and ventilation during handling.

• Transport confirmation: UN number, hazard class, packing group, labels and shipping documents should be verified before shipment according to the latest SDS and DGM.

Related Applications

N,N-Diisopropylethylamine belongs to the tertiary amino alcohols and hindered amine bases segment as a hindered tertiary amine base. It is different from tertiary amino alcohols because it does not contain hydroxyl functionality, but it is often reviewed together with other tertiary amine products in organic synthesis sourcing.

This product is also related to chloroalkylamine intermediates for quaternization where amine functionality and base-mediated reaction routes may be considered in synthesis planning.

Inquiry Information

To request a quotation for N,N-Diisopropylethylamine CAS 7087-68-5, please provide the required quantity, target specification, destination port or delivery address, preferred trade term, packaging requirement and required documents such as COA or SDS.