Heptaethylene Glycol

Heptaethylene glycol, also known as HO-PEG7-OH, is a discrete polyethylene glycol derivative with exactly seven ethylene oxide units terminated by hydroxyl groups. Its well-defined structure and hydrophilic character make it a valuable building block for constructing functional molecules where precise spacer length and water solubility are required.

Basic Information

CAS No.	5617-32-3
EC No.	227-040-3
Linear Formula	HO(CH2CH2O)7H
Molecular Weight	326.38 g/mol
Appearance	Colorless viscous liquid or oil
Melting Point	17.8–18.8 °C (lit.)
Boiling point	244 °C at 0.6 mmHg (lit.)
Density	1.13 g/mL at 20–25 °C (lit.)
Solubility	Soluble in water and polar organic solvents including chloroform and ethanol
Storage Conditions	Keep in a tightly closed container in a cool, dry and well-ventilated place. Protect from moisture. Store at room temperature.
Chemical Structure

Key Applications

• PEG linker intermediate: Employed as a precise hydrophilic linker with seven ethylene oxide units in the design and synthesis of bioconjugates and PEGylated compounds for pharmaceutical and biomedical research.

• Molecular linker intermediate: Functions as a defined spacer in the construction of functional molecules and advanced intermediates where controlled chain length improves solubility and molecular flexibility.

• Hydrophilic spacer: Applied to introduce hydrophilicity and flexibility into molecular architectures during surface modification studies and specialty material development.

• Fine chemical intermediate: Serves as a building block for the preparation of polyether derivatives and other specialty compounds in organic synthesis and fine chemical manufacturing.

• Process development: Supports custom synthesis projects and route optimization efforts requiring well-characterized polyethylene glycol spacers for pharmaceutical or agrochemical intermediates.

• Consistent product quality: High-purity material meeting 98% specification with reliable batch-to-batch consistency suitable for fine chemical synthesis and research applications.

• Flexible global supply: Support for laboratory-scale, pilot and bulk quantities through established international logistics channels serving customers worldwide.

• SDS and COA support: Comprehensive documentation including SDS and COA provided to assist with quality review, regulatory compliance and international procurement processes.

• Packaging and technical service: Adaptable packaging options matched to order size together with responsive technical communication throughout the sourcing and supply process.

Packaging and Storage

• Packaging: Supplied in laboratory quantities using sealed glass bottles or HDPE containers; larger volumes available in suitable drums or customized liquid packaging upon request.

• Storage: Store in a tightly closed container in a cool, dry, well-ventilated area at room temperature. Protect from moisture as the product is hygroscopic.

• Handling of opened containers: Minimize exposure to air and moisture after opening; use contents promptly and reseal containers carefully to maintain product quality.

Safety and Handling

• General handling: Handle in accordance with good industrial hygiene and safety practices. Avoid prolonged or repeated contact with skin and eyes; ensure adequate ventilation during use.

• Personal protection: Wear suitable protective gloves, safety goggles and appropriate clothing when handling to minimize exposure risks.

• Documentation review: Always consult the latest Safety Data Sheet before storage, handling, transportation or use of the product.