Ethyltriphenylphosphonium Bromide

Basic Information of Ethyltriphenylphosphonium Bromide

CAS No.:	1530-32-1
EC No.:	216-223-3
Linear Formula:	C₂H₅P(C₆H₅)₃Br
Molecular Weight:	371.25
Appearance:	White to off-white crystalline powder.
Melting point:	203-205 °C(lit.)
Density:	1.38[at 20℃]
Solubility:	Soluble in various organic solvents, including dichloromethane, tetrahydrofuran (THF), and alcohols. Sparingly soluble in water.
Nature:	A phosphonium salt that forms a reactive ylide when treated with a strong base. The ylide is sensitive to moisture and air.
RIDADR:	UN 3464 6.1/PG 3
Chemical Structure:

Our commitment to delivering high-purity Ethyltriphenylphosphonium Bromide ensures a reliable and efficient component for your critical chemical syntheses, offering consistent quality for diverse research and industrial needs.

Primary Applications of Ethyltriphenylphosphonium Bromide

This specialized Wittig reagent's unique reactivity profile makes it an indispensable tool in advanced organic synthesis, particularly for the precise construction of carbon-carbon double bonds:

1. Wittig Reaction for Olefin Synthesis:

   Its primary application is as a key reagent in the Wittig reaction. When deprotonated by a strong base, it forms an ethylidene triphenylphosphorane ylide. This ylide then reacts with aldehydes or ketones to form new carbon-carbon double bonds, synthesizing olefins (alkenes) with high selectivity.

2. Pharmaceutical and Agrochemical Synthesis:

   The ability to precisely form specific olefins makes it invaluable in the synthesis of complex organic molecules. This includes intermediates for pharmaceuticals, agrochemicals, and other fine chemicals where controlled carbon chain elongation and double bond formation are essential.

3. Flavors and Fragrances Production:

   It is used in the synthesis of specific olefinic compounds that serve as building blocks for various flavors and fragrances, contributing to the development of new aromatic profiles.

4. Polymer and Material Science:

   In some specialized areas of polymer chemistry and material science, it can be used to introduce specific ethylidene functionalities into polymeric structures or monomers.

• Exceptional Purity & Reactivity: Our Ethyltriphenylphosphonium Bromide is manufactured to stringent purity specifications, crucial for ensuring high yields and selectivity in sensitive Wittig reactions and other complex organic syntheses.

• Commitment to Quality & Safety: We adhere to the highest industry standards for quality management, safety, and environmental responsibility across all our operations, ensuring peace of mind for our clients.

Hazards Classification

• GHS Classification: Acute Toxicity (GHS06), Skin Irritation (GHS07), Eye Irritation (GHS07)

• Hazard Statements: Harmful if swallowed; causes skin irritation; causes serious eye irritation.

• UN Number: UN 3464

• Hazard Class: 6.1 (Toxic Substances)

• Packing Group: III