MTPP Chloride

Basic Information of MTPP Chloride

CAS No.:	4009-98-7
EC No.:	223-664-5
Linear Formula:	[(CH₃O)CH₂]P(C₆H₅)₃Cl
Molecular Weight:	342.8
Appearance:	White to off-white crystalline powder.
Melting point:	185-195 °C (dec.)(lit.)
Density:	Soluble in various organic solvents, including dichloromethane, tetrahydrofuran (THF), and benzene. Reacts with water.
Solubility:	>250°C
Nature:	A phosphonium salt that forms a reactive ylide when treated with a strong base. Sensitive to moisture and air in its ylide form.
RIDADR:	UN 3077 9/PG 3
Chemical Structure:

Our commitment to delivering high-purity (Methoxymethyl)triphenylphosphonium Chloride ensures a reliable and efficient component for your critical chemical syntheses, offering consistent quality for diverse research and industrial needs.

Primary Applications of (Methoxymethyl)triphenylphosphonium Chloride

This specialized Wittig reagent's unique reactivity profile makes it an indispensable tool in advanced organic synthesis, particularly for the precise construction of carbon frameworks:

1. Aldehyde and Ketone Homologation:

   Its primary application is in the Wittig reaction for the homologation of aldehydes and ketones. It effectively converts carbonyl compounds into corresponding enol ethers (e.g., vinyl ethers or cyclic enol ethers) by adding a one-carbon unit (CH₂O).

2. Synthesis of Homologated Aldehydes and Ketones:

   The resulting enol ethers are highly valuable intermediates. They can be readily hydrolyzed under mild acidic conditions to yield new aldehydes or ketones that are one carbon longer than the starting material. This makes it a crucial tool for expanding carbon chains in organic molecules.

3. Versatile Synthetic Intermediate:

   Enol ethers can also be further transformed into a variety of other functional groups, making (Methoxymethyl)triphenylphosphonium Chloride a key component in the synthesis of complex organic molecules, including those with pharmaceutical relevance.

4. Preparation of Functionalized Olefins:

   Beyond simple homologation, its derivatives can be used to introduce specific functionalities into olefins through tailored synthetic routes.

• Exceptional Purity & Reactivity: Our (Methoxymethyl)triphenylphosphonium Chloride is manufactured to stringent purity specifications, crucial for ensuring high yields and selectivity in sensitive Wittig reactions and other complex organic syntheses.

• Commitment to Quality & Safety: We adhere to the highest industry standards for quality management, safety, and environmental responsibility across all our operations, ensuring peace of mind for our clients.

Hazards Classification

• GHS Classification: Acute Toxicity Oral (GHS06), Skin Irritation (GHS07), Eye Irritation (GHS07), Hazardous to the Aquatic Environment Chronic (GHS09)

• Hazard Statements: Harmful if swallowed; causes skin irritation; causes serious eye irritation; toxic to aquatic life with long lasting effects.

• UN Number: UN 3077

• Hazard Class: 9 (Miscellaneous Dangerous Goods)

• Packing Group: III