1,3-Dimethylbutylamine (1,3-DMBA)

1,3-Dimethylbutylamine (1,3-DMBA), CAS 108-09-8, is a branched-chain primary amine. It is also systematically known as 4-Amino-2-methylpentane. This colorless, volatile liquid is a key synthetic building block valued for its unique structure, which imparts specific steric and solubility properties to derivative compounds. It plays a significant role in the production of high-performance intermediates for the pharmaceutical and agrochemical sectors.

Basic Information of 1,3-DMBA

CAS No.:	108-09-8
EC No.:	203-550-4
Linear Formula:	C6H15N
Molecular Weight:	101.19
Appearance:	Colorless to pale yellow clear liquid
Odor:	Strong, pungent, ammonia-like odor
Melting Point:	-40.7°C (estimate)
Boiling Point:	108-110 °C(lit.)
Density:	0.717 g/mL at 25 °C(lit.)
Solubility:	Slightly soluble in water; miscible with common organic solvents like alcohol and ether.
Flash Point:	55 °F
RIDADR:	UN 2379 3/PG 2
Chemical Structure:

Application Overview

1,3-Dimethylbutylamine's unique structure—a primary amine with steric hindrance provided by the methyl groups—makes it indispensable in several specialized chemical manufacturing areas:

• Agrochemical Synthesis: It is a crucial intermediate in the production of various herbicides (weed control) and insecticides. The branched nature often enhances the lipophilicity (fat solubility) and selectivity of the final agrochemical product.

• Pharmaceutical Intermediates: 1,3-DMBA is used in the synthesis of complex pharmacological compounds. Its derivatives are sometimes explored in research for central nervous system agents and other specialized therapeutics where a specific molecular architecture is required.

• High-Performance Solvents and Stabilizers: Derivatives of this amine can function as specialty solvents in non-aqueous systems or as stabilizers in certain rubber and polymer formulations, preventing degradation from heat or oxidation.

• Surface Active Agents: It can be used as a reactant in the preparation of amphoteric surfactants or specialized corrosion inhibitors used in industrial processes.

Hazards Classification

• GHS Classification: Flammable Liquid (GHS02), Acute Toxicity (GHS06), Skin Corrosion/Irritation (GHS05)

• Hazard Statements: Highly flammable liquid and vapor; harmful if swallowed, in contact with skin or if inhaled; causes severe skin burns and eye damage.

• UN Number: UN 2379

• Hazard Class: 3 (Flammable Liquids)

• Packing Group: II