Thionyl Chloride

Basic Information of Trimethylsilyl Chloride

CAS No.:	7719-09-7
EC No.:	231-748-8
Linear Formula:	SOCl₂
Molecular Weight:	118.97
Appearance:	Colorless to pale yellow, fuming liquid.
Odor:	A pungent odor
Melting Point:	-105 °C
Boiling Point:	79 °C(lit.)
Density:	1.64 g/mL at 20 °C
Solubility:	Highly reactive with water (hydrolyzes rapidly to HCl and SO₂, alcohols, carboxylic acids, and amines. Powerful chlorinating and dehydrating agent.
Reactivity:	Highly corrosive to metals in the presence of moisture and to organic tissues.
Corrosivity:	Highly corrosive to metals in the presence of moisture and to organic tissues.
Fuming:	Fumes strongly in moist air.
RIDADR:	UN 1836 8/PG 1
Chemical Structure:

Our commitment to delivering high-purity Thionyl Chloride ensures a reliable and efficient component for your critical processes, offering consistent quality for diverse industrial needs, while prioritizing uncompromising safety in handling and logistics.

Primary Applications of Thionyl Chloride

Thionyl Chloride's unique chemical properties, particularly its efficiency as a chlorinating and dehydrating agent with gaseous byproducts, make it an indispensable reagent with extensive applications across various chemical synthesis pathways:

1. Synthesis of Acyl Chlorides:

   One of its most important uses is in the conversion of carboxylic acids into acyl chlorides (RCOCl). This reaction is highly efficient and clean, making acyl chlorides readily available for subsequent organic reactions, such as ester or amide formation.

2. Synthesis of Alkyl Chlorides:

   It is widely employed to convert alcohols into alkyl chlorides (RCl). This is a preferred method as it avoids rearrangements often seen with other chlorinating agents and produces gaseous byproducts.

3. Pharmaceutical Manufacturing:

   Thionyl Chloride serves as a crucial intermediate and reagent in the synthesis of various active pharmaceutical ingredients (APIs) and their intermediates, particularly where precise chlorination or dehydration is required.

4. Agrochemical Production:

   It is used in the synthesis of numerous agrochemicals, including pesticides, herbicides, and fungicides, where chlorine atoms need to be introduced into complex organic molecules.

5. Dye and Pigment Industry:

   Used in the production of certain dyes and pigments, often as a chlorinating agent or for preparing reactive intermediates.

6. Dehydrating Agent:

   Due to its strong affinity for water, it acts as an effective dehydrating agent in specialized chemical reactions and for drying solvents.

7. Other Specialty Chemical Synthesis:

   Plays a role in the synthesis of other specialty chemicals, including fire retardants, polymers, and catalysts.

• Exceptional Purity & Consistent Quality: Our Thionyl Chloride is manufactured to stringent purity specifications, crucial for optimizing performance and yield in sensitive chemical synthesis reactions, such as those in pharmaceutical and fine chemical production.

• Expert Technical & Safety Support: Our dedicated team of experienced chemists and highly trained safety specialists is readily available to offer comprehensive guidance on product application, stringent safe handling procedures, emergency response planning, and optimal storage conditions for Thionyl Chloride.

• Commitment to Quality & Responsible Stewardship: We adhere to the highest industry standards for quality management, environmental responsibility, and product stewardship across all our operations, ensuring peace of mind for our clients and the responsible management of hazardous chemicals.

Hazards Classification

• GHS Classification: Corrosive (GHS05), Acute Toxicity (GHS06), Health Hazard (GHS08)

• Hazard Statements: Causes severe skin burns and eye damage; fatal if inhaled; may cause respiratory irritation; reacts violently with water.

• UN Number: UN 1836

• Hazard Class: 8 (Corrosive Substances)

• Packing Group: I