2-Benzyloxyethanol

2-Benzyloxyethanol, also known as ethylene glycol monobenzyl ether, is a clear liquid specialty chemical with the molecular formula C9H12O2. It functions as a protected hydroxyethyl building block and short-chain PEG derivative, making it useful for constructing functional molecules in fine chemical and research settings.

Basic Information

CAS No.	622-08-2
EC No.	210-719-3
Linear Formula	C6H5CH2OCH2CH2OH
Molecular Weight	152.19 g/mol
Appearance	Colorless to pale yellow clear liquid
Melting Point	< -75 °C (lit.)
Boiling point	265 °C (lit.)
Density	1.071 g/mL at 25 °C (lit.)
Solubility	Soluble in water and polar organic solvents including alcohols and ethers
Storage Conditions	Keep in a tightly closed container in a cool, dry and well-ventilated place. Protect from light. Recommended storage below 15°C or at room temperature.
Chemical Structure

Key Applications

• Organic synthesis intermediate: Employed in multi-step organic syntheses for the introduction of protected hydroxyethyl moieties and ether functionalities in complex molecule assembly.

• Pharmaceutical intermediate: Used as a building block in medicinal chemistry research and the development of active pharmaceutical ingredients requiring specific ether linkages.

• PEG linker intermediate: Functions as a short hydrophilic spacer (BnO-PEG1 unit) in the design of molecular linkers for bioconjugation and surface modification studies.

• Laboratory research: Widely utilized in academic and industrial laboratories for exploring synthetic methodologies and functional group transformations involving protected glycols.

• Process development: Supports route optimization and custom synthesis projects where high-purity specialty intermediates are required for scalable production.

• Consistent product quality: High-purity grades with reliable batch consistency, supported by quality coordination to meet the stringent requirements of fine chemical and research applications.

• Flexible global supply: Stable export capabilities through established logistics networks, accommodating orders from laboratory scale samples to pilot and bulk quantities for international customers.

• SDS and COA support: Full documentation package including Safety Data Sheets and Certificates of Analysis available to assist with compliance, quality review, and export procedures.

• Packaging and technical service: Professional assistance with packaging selection for liquid products and responsive technical communication to address specific sourcing and application needs.

Packaging and Storage

• Packaging: Supplied in laboratory-scale sample bottles (1 kg or 5 kg) and larger commercial packs such as 25 L or 200 L HDPE drums. Customized packaging options are available upon request to suit order volume and handling preferences.

• Storage: Store in tightly sealed containers in a cool, dry, and well-ventilated environment. Protection from light and moisture is recommended, with ideal temperatures at or below room temperature or as specified (<15°C).

• Handling of opened containers: Reseal containers immediately after use and maintain original storage conditions to preserve product integrity. Follow standard chemical handling protocols for liquids.

Safety and Handling

• General handling: Use in well-ventilated areas and avoid direct contact with skin, eyes, or inhalation of vapors. Follow good laboratory and industrial hygiene practices during transfer and processing.

• Personal protection: Wear appropriate personal protective equipment such as chemical-resistant gloves, safety goggles, and protective clothing. Refer to the product SDS for detailed recommendations.

• Documentation review: Review the most current Safety Data Sheet (SDS) and supporting documents prior to any handling, storage, transportation, or use to ensure safe practices and regulatory compliance.