2,6-Lutidine

Basic Information of 2,6-Lutidine

CAS No.:	108-48-5
EC No.:	203-587-3
Linear Formula:	(CH₃)₂C₅H₃N
Molecular Weight:	107.15
Appearance:	Transparent Liquid
Odor:	Pungent, characteristic pyridine odor.
Melting point:	-6 °C (lit.)
Boiling point:	143-145 °C (lit.)
Density:	0.92 g/mL at 25 °C (lit.)
Solubility:	Slightly soluble in water; miscible with most organic solvents like ethanol, ether, and benzene.
Flash point:	92 °F
Nature:	Flammable liquid and vapor, harmful by inhalation and skin contact.
RIDADR:	UN 1993 3/PG 3
Chemical Structure:

Our commitment to delivering high-purity 2,6-Lutidine ensures a reliable and efficient component for your complex manufacturing and synthesis processes.

Primary Applications of 2,6-Lutidine (2,6-Dimethylpyridine)

The unique steric hindrance of the methyl groups adjacent to the nitrogen in 2,6-Lutidine influences its reactivity, making it a highly valued chemical in several key industries:

• Pharmaceutical Synthesis: A key intermediate for APIs, especially where substituted pyridine moieties are required.

• Agrochemicals: Used in the synthesis of herbicides, insecticides, and fungicides, enhancing bioactivity and stability.

• Specialty Polymers: Acts as a monomer/building block for polymers with improved thermal and chemical resistance.

• Non-Nucleophilic Base: Valuable in dehydrohalogenations and base-catalyzed reactions due to steric hindrance of methyl groups.

• Catalyst/Ligand: Functions as a ligand in metal complexes, influencing catalytic performance and material properties.

• Exceptional Purity & Consistency: Our 2,6-Lutidine is manufactured to stringent purity specifications, crucial for maximizing yields in complex syntheses and ensuring consistent quality in your downstream products.

• Commitment to Quality & Safety: We adhere to the highest industry standards for quality management, safety, and environmental responsibility across all our operations, ensuring peace of mind for our clients handling this versatile material.

Frequently Asked Questions

Q1: Is 2,6-Lutidine soluble in water?
A1: It has limited solubility in water but is readily soluble in organic solvents such as ethanol and ether.

Q2: What are the main applications?
A2: Mainly used as a pharmaceutical intermediate and as a base in organic reactions.

Hazards Classification

• GHS Classification: Flammable Liquid (GHS02), Acute Toxicity / Irritant (GHS07), Health Hazard (GHS08)

• Hazard Statements: Flammable liquid and vapor; harmful if swallowed, in contact with skin or if inhaled; causes skin irritation and serious eye irritation; may cause damage to organs through prolonged or repeated exposure.

• UN Number: UN 1993

• Hazard Class: 3 (Flammable Liquids)

• Packing Group: III