1-(3-Chloropropyl)-4-(2-hydroxyethyl)piperazine

1-(3-Chloropropyl)-4-(2-hydroxyethyl)piperazine is a chloroalkyl and hydroxyethyl substituted piperazine derivative used as an organic intermediate in selected pharmaceutical intermediate, fine chemical, and specialty synthesis routes. Its structure contains a piperazine ring with one chloropropyl side chain and one hydroxyethyl side chain, providing both chloroalkyl functionality and alcohol functionality for downstream transformation.

Basic Information

CAS No.	57227-28-8
EC No.	Not available
Linear Formula	C9H19ClN2O
Molecular Weight	206.71
Appearance	Colorless to light yellow liquid or low-melting solid
Melting Point	Not available (typical reference)
Boiling point	Not available (typical reference)
Density	Not available (typical reference)
Solubility	Soluble in common organic solvents
Storage Conditions	Keep in a cool, dry place, sealed tightly, protected from light and moisture
Chemical Structure

Key Applications

• Organic synthesis intermediate: Can be used as a chloropropyl hydroxyethyl piperazine intermediate in selected organic synthesis routes involving nucleophilic substitution, alcohol derivatization, or further functionalization.

• Fine chemical synthesis: May be evaluated in the preparation of specialty compounds and functionalized piperazine derivatives.

• Pharmaceutical intermediate: Used as a piperazine-based intermediate in selected pharmaceutical intermediate synthesis routes, depending on the target structure and specification requirements.

• Research and route development: Suitable for exploratory synthesis, route screening, and intermediate evaluation involving chloroalkyl or hydroxyethyl piperazine structures.

• Specialty synthesis applications: May support process evaluation for fine chemical and specialty intermediate projects where multifunctional piperazine functionality is required.

Related Heterocycle Intermediates

Buyers sourcing chloroalkyl or hydroxyethyl piperazine derivatives may also review related piperazine intermediates such as 1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride CAS 2031-23-4, 1-(2-Hydroxyethyl)piperazine CAS 103-76-4, and 1-(2-Hydroxyethyl)-4-methylpiperazine CAS 5464-12-0.

• Sourcing feasibility review: Availability, lead time, and order quantity are confirmed according to the specific product, supplier batch, current market conditions, and destination requirements.

• SDS and COA support: Available safety data sheets and certificates of analysis can be provided upon request, subject to the specific supplier, batch, and grade.

• Packaging and export coordination: Packaging format, labeling, documentation, and shipping terms can be discussed according to product properties, order quantity, and destination requirements.