4-Piperidinopyridine

4-Piperidinopyridine is a piperidine-substituted pyridine derivative used as a nitrogen-containing heterocyclic intermediate and nucleophilic pyridine catalyst in selected organic transformations. Its structure combines a pyridine ring with a piperidine substituent, making it useful in acylation, esterification, amidation, and related fine chemical synthesis routes.

Basic Information

CAS No.	2767-90-0
EC No.	220-447-7
Linear Formula	C10H14N2
Molecular Weight	162.23
Appearance	White to off-white crystalline solid
Melting Point	78-83 °C (lit.)
Boiling point	164 °C at 13 Torr (lit.)
Density	1.0 g/cm³ (lit., predicted)
Solubility	Soluble in common organic solvents such as methanol and chloroform
Storage Conditions	Keep in a cool, dry place, protected from light and moisture
Chemical Structure

Key Applications

• Organic synthesis intermediate: Used as a piperidine-substituted pyridine building block in selected organic synthesis and specialty intermediate routes.

• Nucleophilic catalysis: May be evaluated as a nucleophilic pyridine catalyst or DMAP alternative in suitable acylation, esterification, amidation, or related transformations.

• Fine chemical synthesis: Supports preparation of specialty chemicals where a pyridine-based catalyst or piperidinyl pyridine structure is required.

• Heterocyclic synthesis: Can be used in route development involving substituted pyridine derivatives and nitrogen-containing heterocyclic intermediates.

• Research and process evaluation: Suitable for exploratory synthesis, method development, and process screening depending on project requirements.

Related Heterocycle Intermediates

Buyers sourcing cyclic amine-substituted pyridine derivatives may also review related products such as 4-Pyrrolidinopyridine CAS 2456-81-7, 4-Morpholinopyridine CAS 2767-91-1, and N-Methyl-4-pyridinamine CAS 1121-58-0.

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