4-Pyrrolidinopyridine

4-Pyrrolidinopyridine is a pyrrolidine-substituted pyridine derivative used as a nitrogen-containing heterocyclic intermediate and nucleophilic pyridine catalyst in selected organic transformations. Its structure combines a pyridine ring with a pyrrolidine substituent, providing useful reactivity for acylation, esterification, amidation, and related fine chemical synthesis routes.

Basic Information

CAS No.	2456-81-7
EC No.	219-534-2
Linear Formula	C9H12N2
Molecular Weight	148.21
Appearance	White to yellow to orange crystalline solid
Melting Point	54-58 °C (lit.)
Boiling point	171-173 °C at 20 mmHg (lit.)
Density	1.06 g/cm³ (lit., predicted)
Solubility	Soluble in methanol and other polar organic solvents
Storage Conditions	Store at room temperature in a cool, dry place, protected from light and moisture
Chemical Structure

Key Applications

• Organic synthesis intermediate: Used as a pyrrolidine-substituted pyridine building block in selected organic synthesis and specialty intermediate routes.

• Nucleophilic catalysis: May be evaluated as a nucleophilic pyridine catalyst or DMAP alternative in suitable acylation, esterification, amidation, or related transformations.

• Fine chemical synthesis: Supports preparation of specialty chemicals where a pyridine-based catalyst or pyrrolidinyl pyridine structure is required.

• Heterocyclic synthesis: Can be used in route development involving substituted pyridine derivatives and nitrogen-containing heterocyclic intermediates.

• Research and process evaluation: Suitable for exploratory synthesis, method development, and process screening depending on project requirements.

Related Heterocycle Intermediates

Buyers sourcing cyclic amine-substituted pyridine derivatives may also review related products such as 4-Piperidinopyridine CAS 2767-90-0, 4-Morpholinopyridine CAS 2767-91-1, and N-Methyl-4-pyridinamine CAS 1121-58-0.

• Sourcing feasibility review: Availability, lead time, and order quantity are confirmed according to the specific product, supplier batch, and current market conditions.

• SDS and COA support: Available safety data sheets and certificates of analysis can be provided upon request, subject to the specific supplier, batch, and grade.

• Packaging and export coordination: Packaging format, labeling, documentation, and shipping terms can be discussed according to product properties, order quantity, and destination requirements.