Biological Buffers

Tris Base

CAS No.
77-86-1
Catalogue ID
GTC-676

Tris Base, CAS 77-86-1. Source-derived identification, physical data and applications are provided for catalogue reference; request the current specification, COA and SDS for the required grade.

Catalogue aliases / related identifiers

TRIS; Tris(hydroxymethyl)aminomethane; Tromethamine; THAM; Trizma Base; 2-Amino-2-(hydroxymethyl)-1,3-propanediol; Trometamol; Trisamine

Supplied catalogue source: GTC-676 · Page 128

Reference data — confirm before ordering or use

The information below is a structured migration from the supplied catalogue snapshot. It is not a current product specification, COA or SDS. Confirm the actual supplier, grade, batch documents, classification, packing and destination requirements for your enquiry.


Basic Information

CAS No.77-86-1
EC No.201-064-4
Linear FormulaC4H11NO3
Molecular Weight121.14 g/mol
AppearanceWhite crystalline powder
Melting Point167-172 °C (lit.)
Boiling point219-220 °C at 10 mmHg (lit.)
Density1.33 g/cm³ (lit.)
SolubilityFreely soluble in water
Storage ConditionsKeep in a tightly closed container in a cool, dry and well-ventilated place.
Chemical StructureMolecular Structure of Tris Base

Key Applications

  • Biological buffer: Tris Base is used to maintain stable pH conditions in biological and biochemical systems where controlled buffering performance is required.

  • Laboratory buffer reagent: The product is commonly applied in the preparation of laboratory buffers for molecular biology experiments and protein studies.

  • Cell culture reagent: Tris Base may be incorporated into cell culture media formulations where pH stability supports consistent experimental conditions.

  • Biochemical assay reagent: It serves as a reliable component in biochemical assays and diagnostic procedures requiring precise pH control.

  • Buffer formulation: The reagent is suitable for custom buffer development and process optimization in research and development laboratories.


  • Consistent product quality: High-purity specifications and batch-to-batch consistency make it suitable for biochemical reagent sourcing and laboratory use.

  • Stable export supply: Reliable international logistics channels support sample, trial and bulk procurement for global customers.

  • SDS and COA support: Standard product documentation including SDS and COA is available upon request for quality review and regulatory compliance.

  • Flexible packaging options: Customized packing solutions and responsive technical communication accommodate small-batch to bulk supply requirements.

Before you order

Confirm the current commercial product record.

Include the required grade or purity, quantity, preferred packing, destination country/port and required document set.

  • 01Current specification
  • 02Batch or sample COA
  • 03Product- and supplier-specific SDS
  • 04Packing and shipping review
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