Isobutylamine

GTC-405

Amines

Isobutylamine

CAS No.
78-81-9
Catalogue ID
GTC-405

Isobutylamine, CAS 78-81-9. Source-derived identification, physical data and applications are provided for catalogue reference; request the current specification, COA and SDS for the required grade.

Catalogue aliases / related identifiers

2-Methylpropan-1-amine; 1-Amino-2-methylpropane; 2-Methylpropylamine; Monoisobutylamine; iso-Butylamine; Valamine; IBA

Supplied catalogue source: GTC-405 · Page 26

Reference data — confirm before ordering or use

The information below is a structured migration from the supplied catalogue snapshot. It is not a current product specification, COA or SDS. Confirm the actual supplier, grade, batch documents, classification, packing and destination requirements for your enquiry.

Isobutylamine is a branched aliphatic primary amine known for its strong nucleophilicity, stability, and versatility in organic synthesis. Its compact branched structure makes it suitable for generating sterically influenced intermediates, contributing to improved molecular performance in pharmaceutical, agrochemical, and polymer applications.


Basic Information of Isobutylamine

CAS No.:78-81-9
EC No.:201-145-4
Linear Formula:C4H11N
Molecular Weight:73.14
Appearance:Clear, colorless to pale yellow liquid
Odor:Strong amine-like odor
Melting Point:-85 °C (lit.)
Boiling Point:64-71 °C (lit.)
Density:0.736 g/mL at 25 °C (lit.)
Solubility:Miscible with most organic solvents; limited water solubility
Flash Point:15 °F
RIDADR:UN 1214 3/PG 2
Chemical Structure:Molecular Structure of Isobutylamine

Application Overview

Isobutylamine finds broad industrial usage thanks to its ease of reactivity and branched molecular structure, which provides unique steric effects valuable in synthesis. It is widely utilized            in pharmaceuticals, crop-protection chemicals, polymer modification, and fine chemical development.

  • Pharmaceutical Intermediates: Used in synthesizing API side chains, active fragments, and stabilizing groups in medicinal chemistry.

  • Agrochemicals: An essential raw material for herbicides, plant-growth regulators, pesticide intermediates, and nitrogen-containing crop protection compounds.

  • Polymer Additives: Applied in resin modification, adhesion promoters, curing systems, and functional monomer production.

  • Organic Synthesis: Suitable for amide formation, reductive amination, alkylation reactions, catalytic reactions, and custom fine chemical development.

  • Rubber & Specialty Chemicals: Used in vulcanization accelerators, specialty stabilizers, fragrances, flavors, and dye intermediates.

  • Laboratory & R&D Applications: Widely adopted in research labs and pilot-scale innovation for creating new amine-based molecules.

Its combination of reactivity, solubility, and molecular branching makes Isobutylamine a highly adaptable choice for both large-scale industrial production and specialized chemical design.


  • Regulatory and Documentation Support: Comprehensive COAs, MSDS, REACH-related documents, and export certifications available on request.

  • Responsive Technical Team: Our specialists offer guidance on application fit, formulation compatibility, and production optimization.


Hazards Classification

  • GHS Classification: Flammable Liquid (GHS02), Corrosive (GHS05), Acute Toxicity (GHS06)

  • Hazard Statements: Highly flammable liquid and vapor; causes severe skin burns and eye damage; harmful if swallowed, in contact with skin, or if inhaled.

  • UN Number: UN 1214

  • Hazard Class: 3 (Flammable Liquids)

  • Packing Group: II

GHS02: flammable pictogram
GHS02: Flammable
GHS05: Corrosive pictogram
GHS05: Corrosive
GHS06: Acute toxicity pictogram
GHS06: Acute toxicity
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