Diisopropylamine

Diisopropylamine (DIPA) is a secondary aliphatic amine known for its moderate basicity, low nucleophilicity, and excellent compatibility with organic synthesis processes. It serves as a valuable building block and catalyst component across pharmaceutical, agrochemical, and fine-chemical manufacturing.

Basic Information of Diisopropylamine

CAS No.:	108-18-9
EC No.:	203-558-5
Linear Formula:	C6H15N
Molecular Weight:	101.19
Appearance:	Colorless to pale yellow transparent liquid
Odor:	Amine.
Melting Point:	-61 °C (lit.)
Boiling Point:	~83–85°C
Density:	~0.72 g/cm³
Solubility:	Miscible with organic solvents; limited solubility in water
Flash Point:	1.4 °F
RIDADR:	UN 1158 3/PG 2
Chemical Structure:

Application Overview

Diisopropylamine is widely applied in industrial and laboratory synthesis due to its steric hindrance, reduced reactivity compared to primary amines, and suitability for non-nucleophilic base applications. Its major uses include:

• Pharmaceutical Synthesis: Key intermediate for APIs, peptide coupling reagents, and protective-group chemistry.

• Non-Nucleophilic Base Reactions: Often converted to lithium diisopropylamide (LDA), a standard strong base in organometallic chemistry.

• Agrochemical Manufacturing: Precursor for pesticide intermediates, herbicide building blocks, and selective crop-protection agents.

• Catalyst and Processing Aid: Utilized in catalytic systems requiring controlled basicity and limited nucleophilicity.

• Fine Chemical Intermediates: Supports synthesis of specialty solvents, stabilizers, and advanced organic materials.

• Polymer and Resin Processing: Applied in producing curing agents, performance modifiers, and functional polymer intermediates.

• Electronic Chemicals: Suitable for precision synthesis steps within semiconductor and microelectronics materials.

• Process-Driven Quality Assurance: Our automated purification and distillation systems ensure narrow impurity profiles, ideal for high-specification chemical processes.

• Stability in Long-Term Contracts: Multi-region production capabilities and secure raw-material partnerships ensure reliable long-term delivery.

• Custom Solution Options: Tailored purity grades, low-water specifications, and specialized packaging formats are available upon request.

• Global Support Network: Regional distribution centers and responsive logistics teams provide efficient fulfillment and responsive after-sales service.

Hazards Classification