2-(2-Methoxyethoxy)acetaldehyde dimethylacetal

2-(2-Methoxyethoxy)acetaldehyde dimethylacetal (CAS 94158-44-8) is a stable acetal derivative that functions as a masked form of 2-(2-methoxyethoxy)acetaldehyde in organic synthesis. The dimethyl acetal group protects the aldehyde during handling while the methoxyethoxy chain provides specific solubility and reactivity profiles for downstream transformations.

Basic Information

CAS No.	94158-44-8
EC No.	303-115-7
Linear Formula	C7H16O4
Molecular Weight	164.20
Appearance	Colorless to light yellow clear liquid
Melting Point	Not available (typical reference)
Boiling point	79-80 °C at 9.9 mmHg (lit.)
Density	1.000 g/mL at 20 °C (lit.)
Solubility	Soluble in common organic solvents
Storage Conditions	Store in a tightly closed container in a cool, dry place. Keep away from heat and ignition sources.
Chemical Structure

Key Applications

• Protected aldehyde intermediate: 2-(2-Methoxyethoxy)acetaldehyde dimethylacetal functions as a stable acetal-protected form of an ether-substituted aldehyde, enabling controlled introduction of the methoxyethoxyacetaldehyde unit in multi-step synthesis. It is widely used in Acetals and Protected Carbonyl Ethers for Organic Synthesis, where masked carbonyl functionality improves stability and selectivity.

• Dual-function acetal and ether structure: The molecule combines acetal protection with a glycol ether chain, providing both reversible carbonyl masking and enhanced solubility or flexibility. This dual functionality is part of the acetal and ether-functional intermediate category.

• Fine chemical and pharmaceutical intermediate: Used in the synthesis of specialty chemicals, pharmaceutical intermediates, and functional molecules where controlled release of aldehyde functionality and ether-based modification are required.

• Functional molecule construction: Facilitates the assembly of complex molecules through acetal chemistry combined with ether chain incorporation, supporting the design of advanced intermediates with tailored physicochemical properties.

• Laboratory research: Widely used in research for synthetic methodology development, particularly in protecting group strategies and ether-modified molecular systems.

• Process development: Supports route optimization and scale-up in processes requiring stable acetal intermediates with tailored ether substituents and controlled deprotection behavior.

2-(2-Methoxyethoxy)acetaldehyde dimethylacetal belongs to the Acetals and Protected Carbonyl Ethers application category and is part of our broader portfolio of Ethers for Pharmaceutical Intermediates & Specialty Synthesis, covering acetal derivatives, protected aldehydes, and ether-functional intermediates for API and fine chemical synthesis.

• Flexible global supply: Stable international logistics support laboratory, pilot, and bulk procurement with reliable delivery to fine chemical customers worldwide.

• SDS and COA support: Full SDS, COA, and regulatory documentation provided upon request to streamline quality review and international procurement.

• Packaging and technical service: Flexible packaging in 25L/200L HDPE drum, accompanied by responsive technical communication for synthesis applications.