1-(2-Hydroxyethyl)imidazole

1-(2-Hydroxyethyl)imidazole is a hydroxyethyl-substituted imidazole derivative used as an organic intermediate in selected pharmaceutical intermediate, fine chemical, and specialty synthesis routes. Its structure combines an imidazole ring with a hydroxyethyl side chain, providing both nitrogen heterocycle character and alcohol functionality for downstream transformation.

Basic Information

CAS No.	1615-14-1
EC No.	216-565-3
Linear Formula	C5H8N2O
Molecular Weight	112.13
Appearance	White to light yellow solid
Melting Point	36-40 °C (lit.)
Boiling point	115 °C (lit.)
Density	1.15 g/mL at 20-25 °C (lit.)
Solubility	Soluble in water and common organic solvents
Storage Conditions	Sealed in dry conditions at room temperature
Chemical Structure

Key Applications

• Organic synthesis intermediate: Can be used as a hydroxyethyl imidazole intermediate in selected organic synthesis routes involving alcohol derivatization, acylation, alkylation, coupling, or further functionalization.

• Heterocyclic synthesis: May be evaluated in route development involving functionalized imidazole derivatives and five-membered nitrogen heterocycle intermediates.

• Pharmaceutical intermediate: Used as an imidazole-based intermediate in selected pharmaceutical intermediate synthesis routes, depending on the target structure and specification requirements.

• Research and route development: Suitable for exploratory synthesis, route screening, and intermediate evaluation involving hydroxyethyl imidazole structures.

• Specialty synthesis applications: May support process evaluation for fine chemical and specialty intermediate projects where N-substituted imidazole or alcohol-functional heterocycle structures are required.

Related Heterocycle Intermediates

Buyers sourcing hydroxyethyl, aminoalkyl, or chloroalkyl imidazole derivatives may also review related imidazole intermediates such as 1-(3-Aminopropyl)imidazole CAS 5036-48-6, 1-(3-Chloropropyl)imidazole CAS 53170-78-4, and 1-Phenethylimidazole CAS 49823-14-5.

For related hydroxyethyl nitrogen heterocycles outside the imidazole series, buyers may also compare 1-(2-Hydroxyethyl)piperazine CAS 103-76-4, 4-(2-Hydroxyethyl)morpholine CAS 622-40-2, and 1-(2-Hydroxyethyl)pyrrolidine CAS 2955-88-6.

• Sourcing feasibility review: Availability, lead time, and order quantity are confirmed according to the specific product, supplier batch, current market conditions, and destination requirements.

• SDS and COA support: Available safety data sheets and certificates of analysis can be provided upon request, subject to the specific supplier, batch, and grade.

• Documentation and export review: Documentation needs, import requirements, and shipment feasibility should be reviewed according to the product, destination market, and intended use.

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