1,11-Diamino-3,6,9-trioxaundecane

The primary amino end groups support efficient coupling chemistry, while the PEG4 segment enhances solubility and reduces steric hindrance in conjugation applications. It is typically supplied as a liquid with purity specifications in the 95% to 99%+ range. This compound serves as a practical building block for researchers and process chemists seeking reliable PEG-based spacers in fine chemical workflows.

Basic Information

CAS No.	929-75-9
EC No.	213-207-2
Linear Formula	H₂N(CH₂CH₂O)₃CH₂CH₂NH₂
Molecular Weight	208.26 g/mol
Appearance	Colorless to pale yellow liquid
Melting Point	Not available (typical reference)
Boiling point	145 °C at 0.05 mmHg (lit.)
Density	~1.04 g/mL at 20 °C (lit.)
Solubility	Soluble in water and polar organic solvents
Storage Conditions	Keep in a tightly closed container in a cool, dry and well-ventilated place. Protect from moisture and incompatible materials.
Chemical Structure

Key Applications

• PEG linker intermediate: The PEG4 chain length offers an extended hydrophilic spacer ideal for PEGylation and bioconjugate preparation where moderate linker distance improves molecular performance.

• Molecular linker intermediate: Serves as a flexible polyether building block for assembling functional organic structures through its terminal amino groups in specialty chemical synthesis.

• Bioconjugation research: Facilitates efficient linking of biomolecules and labels via primary amine coupling, supporting studies in medicinal chemistry and surface modification.

• Fine chemical intermediate: Applied in the development of advanced intermediates requiring a water-soluble diamine spacer for pharmaceutical and specialty synthesis routes.

• Process development: Supports custom synthesis projects and route optimization involving hydrophilic PEG-based diamines for laboratory and pilot-scale work.

• Consistent product quality: High-purity material maintained with reliable batch consistency suitable for fine chemical and research applications.

• Flexible global supply: Support for laboratory, pilot, and bulk quantities through established international logistics and export arrangements.

• SDS and COA support: Comprehensive documentation including SDS and COA is provided to assist with quality assessment, regulatory review, and procurement.

• Packaging and technical service: Responsive technical communication and help with selecting packaging options matched to product form and order volume.

Packaging and Storage

• Packaging: Supplied in small quantity sample bottles, 1 L to 25 L HDPE drums, and customized liquid packaging options upon request.

• Storage: Store in tightly closed containers in a cool, dry, and well-ventilated area, protected from moisture and incompatible substances.

• Handling of opened containers: Minimize air and moisture exposure after opening; reseal promptly and use contents within recommended timeframes.

• Bulk supply: Flexible packaging and delivery solutions available for pilot-scale and larger commercial orders.

Safety and Handling

• General handling: Follow good industrial hygiene practices. Avoid direct contact with skin, eyes, and clothing during handling and transfer operations.

• Personal protection: Wear suitable personal protective equipment including chemical-resistant gloves, safety goggles, and appropriate protective clothing.

• Documentation review: Consult the latest Safety Data Sheet prior to any handling, storage, transportation, or use of the product.

• Compatibility: Evaluate compatibility with other process materials and avoid exposure to strong oxidizing agents or conditions that could affect amine groups.