N-(2-Hydroxyethyl)nicotinamide

N-(2-Hydroxyethyl)nicotinamide is a nicotinamide derivative featuring a hydroxyethyl side chain attached to the pyridine-3-carboxamide core. This structure makes it a useful building block in the construction of more complex heterocyclic molecules.

Basic Information

CAS No.	6265-73-2
EC No.	Not available
Linear Formula	C8H10N2O2
Molecular Weight	166.18
Appearance	White to off-white solid
Melting Point	92 °C (lit.)
Boiling point	185-195 °C (lit., at reduced pressure)
Density	1.212 g/cm³ (Predicted)
Solubility	Soluble in water and alcohols (typical reference)
Storage Conditions	Keep in a cool, dry place, protected from light and sealed tightly
Chemical Structure

Key Applications

• Pharmaceutical intermediate: Used as a nicotinamide-derived intermediate in selected pharmaceutical intermediate synthesis and fine chemical routes.

• Organic synthesis intermediate: Supports the introduction of hydroxyethyl amide functionality in multi-step organic transformations.

• Heterocyclic synthesis: Can be used in the preparation of substituted pyridine derivatives and related nitrogen-containing heterocyclic intermediates.

• Research and route development: Suitable for exploratory synthesis, route screening, and intermediate evaluation depending on project requirements.

• Fine chemical development: May support route optimization and scale-up evaluation for fine chemical and specialty synthesis applications.

Related Heterocycle Intermediates

Buyers sourcing hydroxyethyl or pyridine-based nitrogen heterocycle intermediates may also review related products such as N-Methyl-4-pyridinamine CAS 1121-58-0, 4-(Octylamino)pyridine CAS 64690-19-3, and 1-(2-Hydroxyethyl)piperazine CAS 103-76-4.

• Sourcing feasibility review: Availability, lead time, and order quantity are confirmed according to the specific product, supplier batch, and current market conditions.

• SDS and COA support: Available safety data sheets and certificates of analysis can be provided upon request, subject to the specific supplier and batch.

• Packaging and export coordination: Packaging format, labeling, documentation, and shipping terms can be discussed according to product properties, order quantity, and destination requirements.