4-(2-Hydroxyethyl)morpholine

4-(2-Hydroxyethyl)morpholine is a hydroxyethyl-substituted morpholine derivative used as an organic intermediate in selected pharmaceutical intermediate, fine chemical, and specialty synthesis routes. Its structure combines a morpholine ring with a primary alcohol group on an ethyl chain, providing both O,N-containing heterocyclic character and hydroxyl functionality for downstream transformation.

Basic Information

CAS No.	622-40-2
EC No.	210-734-5
Linear Formula	C6H13NO2
Molecular Weight	131.17
Appearance	Colorless to light yellow clear liquid
Melting Point	-1 °C (lit.)
Boiling point	227 °C (lit.)
Density	1.083 g/mL at 25 °C (lit.)
Solubility	Miscible with water and common organic solvents
Storage Conditions	Keep in a cool, dry place, sealed tightly, protected from moisture
Chemical Structure

Key Applications

• Organic synthesis intermediate: Can be used as a hydroxyethyl morpholine intermediate for introducing morpholinoethyl functionality in selected organic synthesis routes.

• Fine chemical synthesis: May be evaluated in the preparation of esters, ethers, and other derivatives for specialty chemical applications.

• Pharmaceutical intermediate: Used as a morpholine-based intermediate in selected pharmaceutical intermediate synthesis routes, depending on the target structure and specification requirements.

• Research and route development: Suitable for exploratory synthesis, route screening, and intermediate evaluation involving hydroxyethyl morpholine structures.

• Specialty synthesis applications: May support process evaluation for fine chemical and specialty intermediate projects involving alcohol-based coupling or derivatization steps.

Related Heterocycle Intermediates

Buyers sourcing hydroxyethyl or aminoethyl morpholine derivatives may also review related morpholine intermediates such as 4-(2-Aminoethyl)morpholine CAS 2038-03-1, 4-[2-(2-Hydroxyethoxy)ethyl]morpholine CAS 3603-45-0, and 4-(3-Chloropropyl)morpholine CAS 7357-67-7.

• Sourcing feasibility review: Availability, lead time, and order quantity are confirmed according to the specific product, supplier batch, and current market conditions.

• SDS and COA support: Available safety data sheets and certificates of analysis can be provided upon request, subject to the specific supplier, batch, and grade.

• Packaging and export coordination: Packaging format, labeling, documentation, and shipping terms can be discussed according to product properties, order quantity, and destination requirements.