Scandium Triflate

Basic Information of Scandium Triflate

CAS No.:	144026-79-9
EC No.:	629-306-8
Linear Formula:	Sc(CF₃SO₃)₃
Molecular Weight:	492.16
Appearance:	White crystalline solid.
Melting Point:	335-340 °C
Solubility:	Highly soluble in water and many polar organic solvents (e.g., alcohols, acetonitrile, DMF, DMSO).
Stability:	Excellent thermal stability; remarkably stable and active in protic and aqueous environments.
Purity:	Available in high purity grades (e.g., 99% min) for sensitive catalytic applications.
Chemical Structure:

Our commitment to delivering high-purity Scandium Triflate ensures a reliable and efficient component for your critical processes, offering consistent quality for diverse synthetic and industrial applications.

Primary Applications of Scandium Triflate (Scandium(III) Trifluoromethanesulfonate)

Scandium Triflate's strong Lewis acidity and remarkable water-tolerance make it an invaluable catalyst with significant applications in various advanced chemical processes:

1. Lewis Acid Catalyst in Organic Synthesis:

   Scandium Triflate is a highly versatile and powerful Lewis acid catalyst for a broad spectrum of organic reactions, often enabling transformations that are difficult with traditional catalysts. Key applications include:

• Aldol Reactions: Catalyzes both Mukaiyama aldol reactions and direct aldol reactions, often with high stereo- and enantioselectivity.

• Diels-Alder Reactions: Accelerates cycloaddition reactions, leading to the formation of complex cyclic systems.

• Friedel-Crafts Reactions: Promotes alkylation and acylation reactions on aromatic compounds under mild conditions.

• C-C Bond Forming Reactions: Essential for various carbon-carbon bond forming processes, including Mannich reactions, Michael additions, and allylation reactions.

• Hydrolysis and Glycosylation: Acts as an efficient catalyst for the hydrolysis of acetals and ketals, and for glycosylation in carbohydrate chemistry.

2. Water-Tolerant Catalyst:

   One of its most significant advantages is its water-tolerance. Unlike many other Lewis acids that are deactivated by water, Scandium Triflate maintains or even enhances its activity in the presence of water, facilitating reactions in aqueous or mixed aqueous/organic media, which is crucial for green chemistry and industrial scalability.

3. Reusable Catalyst:

   Its stability often allows for easy recovery and reusability in many catalytic systems, contributing to more sustainable and cost-effective synthetic processes.

4. Pharmaceutical and Agrochemical Synthesis:

   Scandium Triflate is a crucial catalyst in the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals, enabling highly selective and efficient routes to target molecules, particularly those requiring chiral control.

5. Polymer Chemistry and Material Science:

   It can be used as a catalyst in certain polymerization reactions and in the synthesis of advanced materials where precise control over molecular architecture is required.

Its catalytic role is discussed in detail in metal triflates as Lewis acid catalysts in organic synthesis.

For context on how metal triflates function within triflate-based chemistry, see the overview of triflic acid and triflate chemistry.

• Exceptional Purity & Consistent Quality: Our Scandium Triflate is manufactured to stringent purity specifications, crucial for achieving optimal and reproducible catalytic performance in sensitive organic syntheses and demanding industrial processes.

• Expert Technical Support: Our dedicated team of specialists is readily available to offer comprehensive guidance on product application, safe handling, optimal storage, and usage in your specific chemical processes, ensuring maximum efficiency and safety.

• Commitment to Quality & Responsible Stewardship: We adhere to the highest industry standards for quality management, environmental responsibility, and product stewardship across all our operations, ensuring peace of mind for our clients and sustainable sourcing practices.

• Customized Solutions: We understand that different applications may require specific purity levels or particle sizes. We are open to discussing customized solutions to meet your exact requirements.