GHS Classification: Flammable Liquid (GHS02), Exclamation Mark (GHS07)
Hazard Statements: Highly flammable liquid and vapor; may cause skin and eye irritation.
UN Number: UN 2924
Hazard Class: 3 (Flammable Liquids)
Packing Group: II
GTC-640

Linear Siloxanes
Tetramethyldisiloxane (TMDSO)
- CAS No.
- 3277-26-7
- Catalogue ID
- GTC-640
Tetramethyldisiloxane (TMDSO), CAS 3277-26-7. Source-derived identification, physical data and applications are provided for catalogue reference; request the current specification, COA and SDS for the required grade.
TMDSO; TMDS; DMDO; sym-Tetramethyldisiloxane; Dimethylsilyl ether; 1,3-Dihydrotetramethyldisiloxane; 1,1,3,3-Tetramethyldisiloxane; Disiloxane, 1,1,3,3-tetramethyl-
Supplied catalogue source: GTC-640 · Page 53
Reference data — confirm before ordering or use
The information below is a structured migration from the supplied catalogue snapshot. It is not a current product specification, COA or SDS. Confirm the actual supplier, grade, batch documents, classification, packing and destination requirements for your enquiry.
Tetramethyldisiloxane (TMDSO) is a crucial organosilicon compound with the chemical formula (CH₃)₂HSi-O-SiH(CH₃)₂. It presents as a clear, colorless liquid, characterized by low viscosity, high volatility, and excellent chemical stability. The unique aspect of TMDSO lies in its molecular structure, which contains two active silicon-hydrogen (Si-H) bonds. This feature makes it a versatile chemical intermediate, demonstrating superior performance in a wide range of reactions.
Basic Information of Tetramethyldisiloxane
| CAS No.: | 3277-26-7 |
|---|---|
| EC No.: | 221-906-4 |
| Linear Formula: | (CH₃)₂HSi-O-SiH(CH₃)₂ |
| Molecular Weight: | 134.32 |
| Appearance: | Transparent Liquid |
| Melting Point: | <-78°C |
| Boiling point: | 70-71 °C (lit.) |
| Density: | 0.76 g/mL at 25 °C (lit.) |
| Solubility: | Soluble in Chloroform |
| Flash Point: | 14 °F |
| RIDADR: | UN 2924 3/PG 2 |
| Chemical Structure: | ![]() |
Applications of TMSO
Due to its distinctive chemical structure and reactivity, TMDSO plays a pivotal role in numerous industrial sectors and research applications:
Organosilicon Materials:
An essential monomer or cross-linking agent for hydrosilylation reactions, used in the synthesis of various organosilicon polymers, silicone rubbers, and silicone resins.
Utilized in the preparation of functional organosilicon materials with specialized properties.
Pharmaceutical and Agrochemical Intermediates:
Serves as an important silylating agent, used to protect or modify organic molecules containing hydroxyl, amino, and other functional groups.
Acts as a reducing agent or a reactant for specific reactions in drug synthesis.
Fine Chemicals:
Employed as a coupling agent to enhance interfacial adhesion between inorganic fillers and organic polymers.
Used as a selective reducing agent in certain organic synthesis reactions.
Can function as a diluent or solvent for specific systems.
Analytical Applications:
Can be used as a gas chromatography (GC) stationary phase for the separation and analysis of organic compounds.
Used as a reference substance or a solvent component in Nuclear Magnetic Resonance (NMR) spectroscopy.
Surface Treatment:
Applied for the hydrophobization of material surfaces, improving their water repellency.
Exceptional Quality: We commit to providing high-purity TMDSO, ensuring consistency and success in your experiments and production processes.
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Expert Technical Support: Our professional team is readily available to provide product information and technical consultation.
Hazards Classification


Confirm the current commercial product record.
Include the required grade or purity, quantity, preferred packing, destination country/port and required document set.
- 01Current specification
- 02Batch or sample COA
- 03Product- and supplier-specific SDS
- 04Packing and shipping review
