Dimethyl Sulfate

Basic Information of Dimethyl Sulfate

Dimethyl Sulfate (CAS No. 77-78-1) is meticulously produced to meet stringent quality standards, ensuring exceptional purity and consistent performance for your demanding methylation reactions:

CAS No.:	77-78-1
EC No.:	201-058-1
Linear Formula:	(CH₃O)₂SO₂
Molecular Weight:	126.13
Appearance:	Transparent Liquid
Odor:	Faint, onion-like odor (but often described as odorless when pure, strong odor is a sign of impurities or decomposition).
Melting Point:	-32 °C
Boiling point:	188 °C(lit.)
Density:	1.333 g/mL at 25 °C(lit.)
Solubility:	Slightly soluble in water (hydrolyzes slowly); miscible with most organic solvents like alcohols, ethers, ketones, and aromatic hydrocarbons.
Flash Point:	182 °F
Purity:	Corrosive, toxic, and a strong methylating agent.
RIDADR:	UN 1595 6.1/PG 1
Chemical Structure:

Our commitment to delivering high-purity Dimethyl Sulfate ensures a reliable and efficient component for your complex chemical syntheses.

Primary Applications of Dimethyl Sulfate (DMS)

Dimethyl Sulfate's strong electrophilic methylation capability makes it an invaluable reagent for introducing methyl groups into various substrates across numerous industries:

1. Pharmaceutical Synthesis:

   DMS is extensively used in the synthesis of active pharmaceutical ingredients (APIs) and pharmaceutical intermediates. It enables the methylation of nitrogen, oxygen, and sulfur atoms in complex organic molecules, which is critical for creating specific drug structures and modifying their pharmacological properties.

2. Dyes and Pigments Industry:

   It plays a crucial role in the production of various dyes, particularly those used in textiles, leather, and paper. DMS is used to methylate precursors, affecting the color, stability, and fastness properties of the final dye products.

3. Agrochemical Manufacturing:

   DMS is employed in the synthesis of agrochemicals, including certain herbicides, insecticides, and fungicides. Methylation is often a key step in creating effective and selective crop protection agents.

4. Specialty Chemicals & Fine Chemicals:

   As a versatile methylating agent, DMS is used in the production of a wide range of specialty chemicals and fine chemicals. This includes the synthesis of quaternary ammonium salts, methyl esters, methyl ethers, and other derivatives for various industrial applications.

5. Surfactant Production:

   In certain cases, DMS is used to create methylated derivatives of surfactants, modifying their foaming, emulsifying, or wetting properties for specific detergent and personal care formulations.

• Exceptional Purity & Reactivity: Our Dimethyl Sulfate is manufactured to the highest purity standards, ensuring optimal and predictable reactivity in your critical methylation processes.

• Commitment to Quality & Safety: We adhere to the highest industry standards for quality management, safety, and environmental responsibility across all our operations, ensuring peace of mind for our clients.

Hazards Classification

• GHS Classification: Acute Toxicity (GHS06), Corrosive (GHS05), Health Hazard (GHS08), Environmental Hazard (GHS09)

• Hazard Statements: Toxic if inhaled, swallowed, or in contact with skin; causes severe skin burns and eye damage; may cause genetic defects and cancer; very toxic to aquatic life with long lasting effects.

• UN Number: UN 1595

• Hazard Class: 6.1 (Toxic Substances)

• Packing Group: I