3-Chloropropyl 4-Methoxyphenyl Ether

3-Chloropropyl 4-Methoxyphenyl Ether (CAS 20744-03-0) is a bifunctional aromatic ether containing a reactive chloropropyl chain linked to a methoxy-substituted benzene ring. This structure provides a versatile alkylating agent for the extension of aryloxypropyl chains in organic synthesis.

Basic Information

CAS No.	20744-03-0
EC No.	Not available
Linear Formula	C10H13ClO2
Molecular Weight	200.66
Appearance	Colorless to light yellow clear liquid
Melting Point	Not available (typical reference)
Boiling point	301.2±17.0 °C (predicted)
Density	Not available (typical reference)
Solubility	Soluble in common organic solvents
Storage Conditions	Store in a tightly closed container in a cool, dry place. Protect from moisture and light.
Chemical Structure

Key Applications

• Reactive alkylation intermediate: 3-Chloropropyl 4-Methoxyphenyl Ether functions as an efficient alkylating agent for introducing the 3-(4-methoxyphenoxy)propyl moiety into target molecules. It is relevant to Alkoxy Propanols and Propylene Glycol Ethers for Pharmaceutical Synthesis, where alkoxy-functional intermediates enable controlled chain extension and molecular modification.

• Chloroalkyl functionalization: The terminal chloride group provides a reactive handle for nucleophilic substitution, allowing further transformation into amines, ethers, and other functional groups. This reactivity is part of the alkoxy ether application category.

• Fine chemical intermediate: Employed in the synthesis of specialty chemicals and pharmaceutical intermediates requiring stepwise functionalization and controlled structural modification.

• Functional molecule construction: Facilitates assembly of substituted aromatic systems through nucleophilic displacement reactions, supporting the design of advanced functional molecules and linkers.

• Laboratory research: Widely used in research for synthetic route development, linker design, and exploration of bioactive molecules involving aryl ether structures.

• Process development: Supports route optimization and scale-up in processes requiring reliable chloroalkyl aryl ether intermediates with consistent reactivity.

3-Chloropropyl 4-Methoxyphenyl Ether belongs to the Alkoxy Propanols & Glycol Ethers application category and is part of our broader portfolio of Ethers for Pharmaceutical Intermediates & Specialty Synthesis, covering alkoxy-functional intermediates, reactive linkers, and ether-based building blocks for API and fine chemical synthesis.

• Flexible global supply: Reliable international logistics channels provide stable supply from laboratory scale to bulk procurement for fine chemical customers worldwide.

• SDS and COA support: SDS, COA, and complete technical documentation available upon request to streamline sourcing and compliance procedures.

• Packaging and technical service: Packaging in 25L/200L HDPE drum, supported by professional technical communication for application-specific needs.