1-(Benzyloxy)-3-chloropropane

1-(Benzyloxy)-3-chloropropane is a clear liquid alkylating agent featuring a benzyl-protected hydroxyl group and a terminal chloride. It is widely used to introduce the 3-benzyloxypropyl moiety in organic synthesis.

Basic Information

CAS No.	26420-79-1
EC No.	814-938-0
Linear Formula	C10H13ClO
Molecular Weight	184.66
Appearance	Colorless to pale yellow clear liquid
Melting Point (°C)	Not available (typical reference)
Boiling Point (°C)	131-133 (20 Torr) (lit.)
Density (g/mL at 20–25 °C)	1.067 (lit.)
Solubility	Soluble in common organic solvents; slightly soluble in water
Storage Conditions	Store at 2-8°C in a tightly closed container under inert atmosphere
Chemical Structure

Key Applications

• Pharmaceutical intermediate: Used in the synthesis of various pharmaceutical compounds through nucleophilic substitution of the chloride group.

• Organic synthesis intermediate: Serves as an effective reagent for introducing protected hydroxypropyl chains into target molecules.

• Fine chemical intermediate: Applied in the preparation of specialty chemicals and advanced intermediates requiring selective alkylation.

• Laboratory research: Utilized in medicinal chemistry for the development of new bioactive compounds.

• Process development: Supports scale-up of synthetic routes involving protected functional group installation.

• Consistent product quality: Reliable high-purity material ensured through systematic quality control for reproducible synthetic performance.

• Flexible global supply: Stable international delivery options for research quantities through to commercial scale requirements.

• SDS and COA support: Full documentation package including SDS and COA provided to facilitate regulatory compliance and quality assurance.

• Packaging and technical service: Customized liquid packaging in HDPE drums and lab sample bottles with dedicated technical support.