1,3-Dimethoxy-2-propanol

Basic Information

CAS No.	623-69-8
EC No.	801-583-1
Linear Formula	C5H12O3
Molecular Weight	120.15
Appearance	Colorless to light yellow clear liquid
Melting Point	Not available (typical reference)
Boiling point	169 °C (lit.)
Density	1.01 g/mL at 20 °C (lit.)
Solubility	Soluble in water and most organic solvents
Storage Conditions	Sealed in dry, room temperature; store in a tightly closed container in a cool, dry place
Chemical Structure

Key Applications

• Organic synthesis intermediate: 1,3-Dimethoxy-2-propanol functions as a versatile building block and polar solvent in a wide range of organic transformations. It is commonly used in Acetals and Protected Carbonyl Ethers for Organic Synthesis, where dimethoxy-functionalized structures play key roles in reactivity control and intermediate stability.

• Protecting group chemistry: This compound is relevant in protecting group strategies and acetal-type transformations, particularly in reactions involving carbonyl protection and controlled functional group manipulation. These applications are part of the  acetal and dimethoxy ether application category.

• Fine chemical intermediate: Used in the manufacture of specialty chemicals, pharmaceutical intermediates, and agrochemical derivatives, especially where polarity and solubility tuning are required.

• Functional molecule construction: Enables the introduction of dimethoxypropyl motifs into complex functional molecules, supporting the design of advanced intermediates with tailored physicochemical properties.

• Laboratory research: Ideal for laboratory-scale experiments, method development, and exploratory synthesis, particularly in acetal chemistry and functional group protection strategies.

• Process development: Supports route development, pilot-scale synthesis, and scalable production of custom intermediates in both pharmaceutical and specialty chemical manufacturing.

1,3-Dimethoxy-2-propanol belongs to the Acetals and Protected Carbonyl Ethers application category and is part of our broader portfolio of Ethers for Pharmaceutical Intermediates & Specialty Synthesis, covering acetal derivatives, protecting group chemistry, and ether-based intermediates for API and fine chemical synthesis.

• SDS and COA support: Full SDS, COA, and technical documentation packages are available upon request to facilitate quality assurance, regulatory compliance, and export processes.

• Packaging and technical service: Flexible packaging in 1 kg, 5 kg, and 25 kg HDPE drums with PE liner, along with responsive technical assistance tailored to your project specifications.