Tetraethylene Glycol Dichloride

Tetraethylene Glycol Dichloride is a bifunctional alkyl halide derived from polyethylene glycol, widely utilized as an organic intermediate in fine chemical synthesis. It serves as an effective alkylating agent for the introduction of tetraethylene glycol linkages in complex molecular frameworks through nucleophilic substitution reactions.

Basic Information

CAS No.	638-56-2
EC No.	Not available
Linear Formula	Cl(CH2CH2O)4Cl
Molecular Weight	231.12
Appearance	Colorless to pale yellow liquid
Melting Point	Not available (typical reference)
Boiling point	Not available (typical reference)
Density	1.18 g/mL at 20 °C (lit.)
Solubility	Slightly soluble in water; soluble in common organic solvents
Storage Conditions	Keep in a tightly closed container in a cool, dry, well-ventilated place away from heat and ignition sources
Chemical Structure

Key Applications

• Organic synthesis intermediate: Tetraethylene Glycol Dichloride functions as a reactive bifunctional alkylating agent for the introduction of tetraethylene glycol linkages in nucleophilic substitution reactions.

• Fine chemical intermediate: It is employed in the synthesis of specialty chemicals and derivatives requiring flexible PEG-like spacers within fine chemical manufacturing.

• Molecular linker intermediate: The compound enables precise incorporation of hydrophilic tetraethylene glycol chains into target organic frameworks.

• Laboratory research: Tetraethylene Glycol Dichloride supports synthetic methodology studies and reaction development in research laboratories.

• Process development: It aids route optimization and pilot-scale synthesis for advanced organic intermediates.

• SDS and COA support: SDS, COA, and supporting product documents are available upon request to meet sourcing, export, and quality review requirements.

• Packaging and technical service: Assistance with packaging selection is provided alongside flexible options such as 25L/200L HDPE drum, moisture-protected and responsive technical communication.